Update on LogicBio proposed initial public offering in the United States

10th October 2018

THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION WITHIN THE MEANING OF THE EU MARKET ABUSE REGULATION NO.596/2014

LONDON, 10 October 2018: Arix Bioscience plc (LSE:ARIX) (“Arix”), a global healthcare and life science company supporting medical innovation, today notes that LogicBio Therapeutics Inc.(“LogicBio”) has filed an amended registration statement on Form S-1 with the U.S. Securities and Exchange Commission (the “SEC”) relating to a proposed initial public offering in the United States of shares of its common stock.

The registration statement discloses an indicative pricing range for the proposed offering of U.S.$12.00– U.S.$14.00 per common share. This would represent an increase in value of Arix’s current shareholding in LogicBio (compared to the £4.9 million sterling holding value) of £15.9 – £19.4 million[1]. The proposed maximum aggregate offering amount specified in the filing is U.S.$75.0 million, which assumes that the offering price is at the midpoint of the indicative pricing range and does not include the underwriters’ option to purchase additional common shares.

Arix has indicated an interest in purchasing common shares in the offering, subject to agreement with the underwriters.

The registration statement can be accessed through the SEC’s EDGAR database. The registration statement relating to the shares of common stock has been filed with the SEC but has not yet become effective. The shares may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective.

This announcement does not constitute an offer to sell or the solicitation of an offer to buy securities, and shall not constitute an offer, solicitation or sale in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of that jurisdiction.

The securities referred to in this release are to be offered only by means of a prospectus. When available, copies of the preliminary prospectus can be obtained from Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, or by telephone at (877) 821-7388, or by email at Prospectus_Department@Jefferies.com.

[1] At exchange rate on 9 October 2018

ENDS